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Year : 2019  |  Volume : 20  |  Issue : 2  |  Page : 95-98

A study to evaluate the efficacy of topical quick penetrating solution of heparin in preventing thrombophlebitis

Department of Anaesthesiology and Critical Care, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana, India

Correspondence Address:
Dr. Teena Bansal
19/6 J, Medical Campus, PGIMS, Rohtak - 124 001, Haryana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/TheIAForum.TheIAForum_73_18

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Background and Aims: Superficial thrombophlebitis is the most common complication with intravenous cannulation which is characterized by cord-like painful veins and discoloration of skin over puncture site. The study was conducted to evaluate the efficacy of topical quick penetrating solution (QPS) of heparin to prevent superficial thrombophlebitis. Methods: This prospective randomized study included 200 patients who were divided into two groups. In Group I (control group), cannula site was observed using Phlebitis Assessment Grading Scale at 12, 24, 48, and 72 h. In Group II (heparin group), QPS of heparin was applied 12 hourly for up to 72 h, and cannula site was examined at the same time intervals as in Group I. Results: In Group I, at 12 h, score of 0 and 1 was observed in 96 and 4 patients, respectively, whereas all patients had a score of 0 in Group II (P = 0.044). At 24 h, the score was 0, 1, and 2 in 28, 60, and 12 patients, respectively, in Group I, whereas it was 0 and 1 in 96 and 4 patients in Group II (P = 0.001). At 48 h, the score was 1 and 2 in 36 and 64 patients in Group I, whereas it was 0 and 1 in 60 and 40 patients in Group II (P = 0.001), respectively. At 72 h, the score of 2, 3, and 4 was observed in 32, 44, and 24 patients in Group I, respectively, whereas the score of 0, 1, and 2 was observed in 36, 48, and 16 patients, respectively, in Group II (P = .001). Conclusion: Heparin QPS when applied prophylactically significantly decreased thrombophlebitis.

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