Quiz on Pharmacotherapy of Pain

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Pharmacotherapy of Pain: Quiz-2

Prepared by Dr. Athma Prasanna

Royal Hospital Muscat, Sultanate of Oman

(Posted 22nd July, 2007)

Question 1. Respiratory depression due to epidural opioids is controlled with: Naloxone Support ventilation Oxygen All of the above	Question 2.All Opioids are suitable for continuous intravenous infusion except: Morphine Fentanyl Remifentanyl Buprenorphine
Question 3. Anticonvulsants are useful anlgesics: As sole analgesic agents As adjuvant agents As placebos None of the above	Question 4. Antidepressants drugs: Have strong analgesic properties Have no analgesic property Have mild analgesic property None of the above
Question 5. Loading dose is administered in following routes except: PCA I.V. infusions Transdermal Subcutaneous infusions	Question 6. Analgesic Anti inflammatory property of NSAID is due to inhibition of: COX1 enzyme COX2 enzyme COX3 enzyme All of the above
Question 7. Nausea and Vomiting are more with: Buprenorphine Pentazocine Morphine Tramodol	Question 8. Following are Neuraxial opioids except: Morphine Buprenorphine Alfentanyl Remifentanyl
Question 9. NSAID prevent synthesis of except: Prostaglandins PGE2 Thromboxanes Lipoxygenase PGF2a	Question 10. The following statements are true except: First half life of drug control rates of accumulation of drug Steady state is equilibrium between drug input & output Min. effective analgesic conc. provides better analgesia Max. plasma conc. of analgesic provides better analgesia

References & Bibliography

JJ Bonica. The Management of Pain 2nd edition,Lea & Feibeger Pensylvania 1990
Pain 2002-An updated Review Refresher Course Syllabus Ed.M.A. Giameberardino IASP Press Seattle,2002
Munsterhjelm E,. Munsterhjelm, N M, Tomi T. N, M.D., Ph.D., Ylikorkala, O., Neuvonen,PJ,. Rosenberg PH: Dose-dependent Inhibition of Platelet Function by Acetaminophen in Healthy Volunteers Anesthesiology 2005; 103:712–7